Leishmania targets the macrophage epigenome and dampens the NF-κB/NLRP3- mediated inflammatory response
H. Lecoeur, E. Prina, T. Rosazza, K. Kokou, P. N'Diaye, N. Aulner, G. Bussotti, H. Varet, R. Weil, Y. Xing, G. X. Meng, G. F. Spaeth
This study shows Leishmania amazonensis modulates macrophage epigenetics to suppress NF-κB and NLRP3 inflammasome activation, aiding parasite survival.
bioRxiv · May 24, 2019 · PreprintCell Biology