Author

K. Koles

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 3 Organism:Drosophila· 2 Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

A. A. Rodal· 3 shared A. Yeh· 2 shared B. A. Stewart· 2 shared E. C. Dresselhaus· 2 shared K. P. Harris· 2 shared A. L. Scalera· 1 shared A. N. Becalska· 1 shared B. Ermanoska· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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3 shared papersCell Biology

A. A. Rodal

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Author profile →

3 papers

Recent·Most cited

ESCRT disruption provides evidence against signaling functions for synaptic exosomes

E. C. Dresselhaus, K. P. Harris, C. R. R. Blanchette, K. Koles, S. J. Del Signore, M. F. Pescosolido, B. Ermanoska, M. Rozencwaig, R. C. Soslowsky, M. J. Parisi, B. A. Stewart, T. J. Mosca, A. A. Rodal

The paper shows that ESCRT disruption in Drosophila motor neurons affects EV cargo release but not their signaling activities, suggesting EVs may primarily serve proteostatic functions.

bioRxiv · Apr 22, 2023 · PreprintCell Biology

Local regulation of extracellular vesicle traffic by the synaptic endocytic machinery

C. R. Blanchette, A. L. Scalera, K. P. Harris, Z. Zhao, K. Koles, A. Yeh, J. K. Apiki, B. A. Stewart, A. A. Rodal

The paper identifies a role for the clathrin-mediated endocytic machinery in maintaining synaptic EV cargo pools, distinct from its canonical functions in synaptic vesicle recycling.

bioRxiv · Aug 4, 2021Cell Biology

Opposing functions for retromer and Rab11 in extracellular vesicle cargo traffic at presynaptic terminals

R. B. Walsh, A. N. Becalska, M. J. Zunitch, T. Lemos, E. C. Dresselhaus, S. M. Lee, S. Wang, B. Isaac, A. Yeh, K. Koles, A. A. Rodal

The paper investigates the opposing roles of retromer and Rab11 in regulating EV cargo traffic at presynaptic terminals in Drosophila, showing they balance cargo loading and removal.

bioRxiv · Oct 1, 2020Cell Biology