Author

K. Broughton

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:human· 3 Research Focus:differential expression· 2 Approach:biophysical modeling· 1 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Assay:flow cytometry· 1

Frequent Co-Authors

M. Sussman· 3 shared F. Firouzi· 2 shared O. Echeagaray· 2 shared R. Adamson· 2 shared W. Dembitsky· 2 shared A. Salazar· 1 shared D. Kubli· 1 shared E. Schaefer· 1 shared

Activity by Year

2019-2019 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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3 shared papersCell Biology

M. Sussman

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3 papers

Recent·Most cited

Human CardioChimeras: Creation of a Novel \"Next Generation\" Cardiac Cell

F. Firouzi, S. Sinha Choudhury, K. Broughton, A. Salazar, M. Sussman

This paper demonstrates the creation and characterization of human CardioChimeras (hCCs) through cell fusion, showing enhanced survival and cardiomyocyte protection properties.

bioRxiv · Oct 7, 2019Cell Biology

Tetraploidy in rodent cardiac stem cells confers enhanced biological properties

K. Broughton, T. Khieu, N. Nguyen, M. Rosa, S. Mohsin, P. Quijada, J. Wang, O. Echeagaray, D. Kubli, T. Kim, F. Firouzi, M. Monsanto, N. Gude, R. Adamson, W. Dembitsky, , M. Sussman

The paper compares ploidy in cardiac interstitial cells between rodents and large mammals, finding species-specific differences in tetraploidy and its functional implications.

bioRxiv · Mar 26, 2019 · PreprintCell Biology

Safety profiling of genetically engineered Pim-1 kinase overexpression for oncogenicity risk in human c-kit+ cardiac interstitial cells

K. Broughton, K. Korski, O. Echeagaray, R. Adamson, W. Dembitsky, Z. Lu, E. Schaefer, M. Sussman

The paper assesses oncogenic risk of Pim-1 kinase overexpression in c-kit+ cardiac interstitial cells using multiple assays and finds no evidence of oncogenic phenotype.

bioRxiv · Jan 16, 2019Cell Biology