Increased Expression of Chondroitin Sulfotransferases following AngII may Contribute to Pathophysiology Underlying Covid-19 Respiratory Failure: Impact may be Exacerbated by Decline in Arylsulfatase B Activity
S. Bhattacharyya, K. Kotlo, J. K. Tobacman
This study shows Ang II increases chondroitin sulfotransferases and sulfated GAGs in vascular smooth muscle cells, which may enhance SARS-CoV-2 adherence and contribute to respiratory failure in Covid-19.
bioRxiv · Jun 25, 2020 · PreprintBiochemistry