Author

J. K. Tobacman

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Assay:metabolomics· 1

Frequent Co-Authors

S. Bhattacharyya· 2 shared I. O-Sullivan· 1 shared J. Tu· 1 shared K. Kotlo· 1 shared Z. Chen· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

5 top collaborators · 7 mutual co-author links

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2 shared papersCancer Biology

S. Bhattacharyya

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2 papers

Recent·Most cited

Exogenous Recombinant N-Acetylgalactosamine-4-Sulfatase (Arylsulfatase B; ARSB) Inhibits Progression of B16F10 Cutaneous Melanomas and Modulates Cell Signaling

S. Bhattacharyya, I. O-Sullivan, J. Tu, Z. Chen, J. K. Tobacman

This study shows that exogenous ARSB treatment reduces B16F10 melanoma tumor size and improves survival by altering chondroitin sulfate levels and modulating cell signaling pathways.

bioRxiv · May 30, 2023Cancer Biology

Increased Expression of Chondroitin Sulfotransferases following AngII may Contribute to Pathophysiology Underlying Covid-19 Respiratory Failure: Impact may be Exacerbated by Decline in Arylsulfatase B Activity

S. Bhattacharyya, K. Kotlo, J. K. Tobacman

This study shows Ang II increases chondroitin sulfotransferases and sulfated GAGs in vascular smooth muscle cells, which may enhance SARS-CoV-2 adherence and contribute to respiratory failure in Covid-19.

bioRxiv · Jun 25, 2020 · PreprintBiochemistry