Alterations in platelet proteome signature and impaired platelet integrin αIIbβ3 activation in patients with COVID-19
L. J. Goudswaard, C. M. Williams, J. Khalil, K. L. Burley, F. Hamilton, D. Arnold, A. Milne, P. A. Lewis, K. J. Heesom, S. J. Mundell, A. D. Davidson, A. W. Poole, I. Hers
This study identifies altered platelet proteome and impaired integrin αIIbβ3 activation in COVID-19 patients, linked to increased platelet-neutrophil aggregates and thromboinflammation.
bioRxiv · Oct 12, 2022 · PreprintCell Biology