Author

L. J. Goudswaard

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Assay:proteomics· 1

Frequent Co-Authors

I. Hers· 2 shared K. J. Heesom· 2 shared A. D. Davidson· 1 shared A. Milne· 1 shared A. Munkacsi· 1 shared A. W. Poole· 1 shared B. Nabet· 1 shared C. M. Williams· 1 shared

Activity by Year

2022-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersCell Biology

I. Hers

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2 papers

Recent·Most cited

Alterations in platelet proteome signature and impaired platelet integrin αIIbβ3 activation in patients with COVID-19

L. J. Goudswaard, C. M. Williams, J. Khalil, K. L. Burley, F. Hamilton, D. Arnold, A. Milne, P. A. Lewis, K. J. Heesom, S. J. Mundell, A. D. Davidson, A. W. Poole, I. Hers

This study identifies altered platelet proteome and impaired integrin αIIbβ3 activation in COVID-19 patients, linked to increased platelet-neutrophil aggregates and thromboinflammation.

bioRxiv · Oct 12, 2022 · PreprintCell Biology

Chemical degradation of BTK/TEC as a novel approach to inhibit platelet function and thrombosis.

J. S. Trory, A. Munkacsi, K. Sledz, L. J. Goudswaard, K. J. Heesom, S. F. Moore, B. Nabet, V. K. Aggarwal, I. Hers

This study shows that chemical degradation of BTK/TEC in human platelets reduces thrombotic function without affecting PAR-1-mediated responses.

bioRxiv · May 30, 2022 · PreprintCell Biology