Signals Generated by Neutrophil Receptors for Danger Molecules Transactivate Allosterically Modulated FFA2R: Distinct response patterns are mediated by modulators recognized by different allosteric receptor sites
S. C. Lind, K. L. Granberg, H. Forsman, C. Dahlgren
The paper investigates how different activation modes of FFA2R in neutrophils—orthosteric and transactivation—respond to allosteric modulators, revealing distinct response patterns.
bioRxiv · Apr 29, 2022 · PreprintCell Biology