Author

K. M. Frain

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:cryo-EM· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:structural biology· 1 Organism:yeast· 1

Frequent Co-Authors

B. P. Pedersen· 2 shared A. Bohush· 1 shared D. L. Stokes· 1 shared E. Dedic· 1 shared E. Olesen· 1 shared L. Nel· 1 shared P. A. Paulsen· 1 shared T. F. Custodio· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 18 mutual co-author links

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2 shared papersBiochemistry

B. P. Pedersen

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2 papers

Recent·Most cited

Conformational changes in the Niemann-Pick Type C1 protein NCR1 drive sterol translocation

K. M. Frain, E. Dedic, L. Nel, A. Bohush, E. Olesen, D. L. Stokes, B. P. Pedersen

This study identifies a glycocalyx in yeast vacuoles and presents cryo-EM structures of NCR1 showing conformational changes that drive sterol translocation across the glycocalyx.

bioRxiv · Sep 8, 2023Biochemistry

Structural comparison of GLUT1 to GLUT3 reveal transport regulation mechanism in Sugar Porter family

T. F. Custodio, P. A. Paulsen, B. P. Pedersen, K. M. Frain

The paper compares the structure of GLUT1 and GLUT3 to explain differences in glucose affinity and identifies structural motifs that regulate transport in the Sugar Porter family.

bioRxiv · Feb 24, 2020 · PreprintBiochemistry