Author

K. M. Nishiguchi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Assay:electrophysiology· 1

Frequent Co-Authors

K. Fujita· 2 shared T. Nakazawa· 2 shared A. Smith· 1 shared E. Cristante· 1 shared F. Miya· 1 shared J. W. Bainbridge· 1 shared R. H. Douglas· 1 shared R. R. Ali· 1 shared

Activity by Year

2019-2020 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 26 mutual co-author links

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2 shared papersBioengineering

K. Fujita

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2 papers

Recent·Most cited

Improved daylight vision following AAV-mediated expression of R9AP in murine rod photoreceptors

K. M. Nishiguchi, K. Fujita, E. Cristante, J. W. Bainbridge, R. H. Douglas, T. Nakazawa, A. Smith, R. R. Ali

This study shows that over-expressing R9AP in rod photoreceptors of mice lacking cone function improves their ability to respond to bright light, suggesting potential for treating cone dysfunction in humans.

bioRxiv · Feb 19, 2020 · PreprintBioengineering

Single AAV-mediated mutation replacement genome editing in limited number of photoreceptors mediate marked visual restoration

K. M. NISHIGUCHI, K. Fujita, F. Miya, S. Katayama, T. Nakazawa

The paper develops an AAV-based genome editing platform to replace mutations in retinal neurons, achieving significant visual restoration in blind mice.

bioRxiv · Dec 1, 2019 · PreprintBioengineering