Vaccine-specific immune responses against Mycobacterium ulcerans infection in a low-dose murine challenge model
K. M. Mangas, A. H. Buultjens, J. L. Porter, S. L. Baines, E. Marion, L. Marsollier, N. J. Tobias, S. J. Pidot, K. M. Quinn, D. J. Price, K. Kedzierska, W. Zeng, D. C. Jackson, B. Y. Chua, T. P. Stinear
This study evaluates a prime-boost vaccine against Mycobacterium ulcerans in mice, finding that both the experimental ER vaccine and BCG provide significant protection through distinct immune profiles.
bioRxiv · Oct 10, 2019Immunology