Author

N. J. Tobias

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Microbiology· 3 Biochemistry· 1 Immunology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 4 Assay:DNA methylation· 3 Research Focus:host-pathogen & immune response· 3 Assay:proteomics· 3 Organism:bacteria (other)· 2 Research Focus:gene regulatory network inference· 2 Organism:mouse· 2 Approach:statistical model· 2

Frequent Co-Authors

S. J. Pidot· 5 shared T. P. Stinear· 5 shared J. L. Porter· 3 shared B. Y. Chua· 2 shared D. C. Jackson· 2 shared E. Marion· 2 shared H. B. Bode· 2 shared K. M. Mangas· 2 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

5 shared papersMicrobiology

S. J. Pidot

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

A marine sponge-associated mycobacterium closely related to Mycobacterium tuberculosis

S. J. Pidot, S. Klatt, L. S. Ates, W. Frigui, F. Sayes, L. Majlessi, H. Izumi, I. R. Monk, J. L. Porter, V. Bennett-Wood, T. Seemann, A. Otter, G. Taiaroa, G. M. Cook, N. West, , T. P. Stinear

This paper describes the discovery of a marine sponge-associated mycobacterium closely related to M. tuberculosis, which shares virulence factors but lacks virulence in mice.

bioRxiv · Jan 23, 2024 · PreprintMicrobiology

Global analysis of biosynthetic gene clusters reveals conserved and unique natural products in entomopathogenic nematode-symbiotic bacteria

Y.-M. Shi, M. Hirschmann, Y.-N. Shi, S. Ahmed, D. Abebew, N. J. Tobias, P. Gruen, J. J. Crames, L. Poeschel, W. Kuttenlochner, C. Richter, J. Herrmann, R. Mueller, A. Thanwisai, S. J. Pidot, , H. B. Bode

The paper analyzes biosynthetic gene clusters in entomopathogenic nematode-symbiotic bacteria to identify conserved and unique natural products and their functional roles.

bioRxiv · Jan 21, 2022Biochemistry

Small RNA directs symbiosis, virulence, and natural products biosynthesis in entomopathogenic bacteria

N. Neubacher, N. J. Tobias, M. Huber, X. Cai, T. Glatter, S. J. Pidot, T. P. Stinear, A. L. Luetticke, K. Papenfort, H. B. Bode

This study identifies ArcZ, an Hfq-dependent sRNA, as essential for small molecule production in entomopathogenic bacteria, revealing its broad regulatory role beyond secondary metabolites.

bioRxiv · Aug 24, 2020 · PreprintMicrobiology

High antibody titres induced by protein subunit vaccines against Buruli ulcer using Mycobacterium ulcerans antigens Hsp18 and MUL_3720

K. M. Mangas, N. J. Tobias, E. Marion, J. Babonneau, L. Marsollier, J. L. Porter, S. J. Pidot, C. Y. Wong, D. C. Jackson, B. Y. Chua, T. P. Stinear

This study evaluates the vaccine potential of M. ulcerans antigens Hsp18 and MUL_3720 in mice, finding high antibody titres but no significant protection against Buruli ulcer.

bioRxiv · Feb 16, 2020Microbiology

Vaccine-specific immune responses against Mycobacterium ulcerans infection in a low-dose murine challenge model

K. M. Mangas, A. H. Buultjens, J. L. Porter, S. L. Baines, E. Marion, L. Marsollier, N. J. Tobias, S. J. Pidot, K. M. Quinn, D. J. Price, K. Kedzierska, W. Zeng, D. C. Jackson, B. Y. Chua, T. P. Stinear

This study evaluates a prime-boost vaccine against Mycobacterium ulcerans in mice, finding that both the experimental ER vaccine and BCG provide significant protection through distinct immune profiles.

bioRxiv · Oct 10, 2019Immunology