Author

K. M. Weeks

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 4 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Approach:experimental assay· 4 Organism:human· 3 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Assay:structural biology· 2 Organism:bacteria (other)· 1 Assay:bulk RNA-seq· 1

Frequent Co-Authors

A. M. Mustoe· 3 shared C. A. Weidmann· 2 shared S. W. Olson· 2 shared A. Ghanbari Niaki· 1 shared A. Gladfelter· 1 shared A.-M. W. Turner· 1 shared C. M. Termini· 1 shared C. Weidmann· 1 shared

Activity by Year

2018-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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3 shared papersBiochemistry

A. M. Mustoe

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Author profile →

5 papers

Recent·Most cited

Structure-first identification of conserved RNA elements that regulate dengue virus genome architecture and replication.

M. A. Boerneke, N. S. Gokhale, S. M. Horner, K. M. Weeks

The paper identifies conserved RNA structures in dengue virus genomes that regulate replication and fitness, revealing their importance in viral function and potential as antiviral targets.

bioRxiv · Oct 10, 2022Biochemistry

Large-scale allosteric switch in the 7SK RNA regulates transcription in response to growth and stress

S. W. Olson, A.-M. W. Turner, J. W. Arney, I. Saleem, C. A. Weidmann, D. M. Margolis, K. M. Weeks, A. M. Mustoe

The paper introduces DANCE-MaP, a chemical probing strategy to characterize RNA structure and dynamics, revealing 7SK RNA's structural switch regulates transcription in response to growth and stress.

bioRxiv · Sep 16, 2021 · PreprintBiochemistry

RNP-MaP: In-cell analysis of protein interaction networks defines functional hubs in RNA

C. A. Weidmann, A. M. Mustoe, P. B. Jariwala, J. M. Calabrese, K. M. Weeks

RNP-MaP maps protein interaction networks on RNAs with single-nucleotide resolution, revealing conserved hubs and functional sites in RNAs like XIST.

bioRxiv · Feb 7, 2020Biochemistry

RNA base pairing complexity in living cells visualized by correlated chemical probing

A. M. Mustoe, N. Lama, P. S. Irving, S. W. Olson, K. M. Weeks

This paper introduces PAIR-MaP, a method to visualize RNA base pairing in cells, revealing complex structures not detectable by conventional methods.

bioRxiv · Apr 3, 2019Biochemistry

mRNA structure determines specificity of a polyQ-driven phase separation

E. M. Langdon, Y. Qiu, A. Ghanbari Niaki, G. McLaughlin, C. Weidmann, T. Gerbich, J. A. Smith, J. M. Crutchley, C. M. Termini, K. M. Weeks, S. Myong, A. Gladfelter

The paper shows that mRNA secondary structures determine RNA-RNA interactions that influence phase separation and compartment identity.

bioRxiv · Mar 7, 2018Cell Biology