Viral mimicry and memory deficits upon microglial deletion of ATRX
Sarfraz Shafiq, Arsham Ghahramani, K. Mansour, Miguel Ángel Peña-Ortiz, Julia Kathryn Sunstrum, Yan Yi Jiang, Megan E. Rowland, Wataru Inoue, Nathalie G. Bérubé
This study shows that deleting ATRX in microglia disrupts chromatin structure, leading to viral mimicry and cognitive deficits in memory tasks.
bioRxiv · May 7, 2024 · PreprintNeuroscience