Arsham Ghahramani

This study shows that deleting ATRX in microglia disrupts chromatin structure, leading to viral mimicry and cognitive deficits in memory tasks.

A Wasserstein GAN trained on three batch-uncorrected mouse epidermal scRNA-seq datasets simulates realistic cells, predicts differentiation via latent arithmetic, and infers gene networks recovering Gata6 targets.

The paper integrates genetic and cell biological data from human iPSC lines to identify intrinsic and extrinsic factors driving inter-individual variability in cell behavior.

The paper investigates how Wnt/beta-catenin signaling in neighboring cells affects transcriptome heterogeneity and proliferative fate in mouse keratinocytes.