Three functionally distinct classes of cGAS proteins in nature revealed by self-DNA-induced interferon responses
K. Mosallanejad, W. Zhou, A. A. Govande, D. Hancks, P. J. Kranzusch, J. C. Kagan
The paper identifies three functional classes of cGAS proteins in mammals based on their self-DNA reactivity and interferon response mechanisms.
bioRxiv · Mar 9, 2022Immunology