M. H. Schierup

TRAILS: tree reconstruction of ancestry using incomplete lineage sorting

TRAILS infers time-resolved population genetics parameters and speciation times using multi-species genome alignments, improving accuracy over previous methods.

Genome-wide coancestry reveals details of ancient and recent male-driven reticulation in baboons

Genomic data from 225 baboons reveal novel inter-species gene flow sites and local admixture effects across different lineages.

Single-cell analysis maps distinct cellular responses to rhizobia and identifies the novel infection regulator SYMRKL1 in Lotus japonicus

Worldwide late-Quaternary population declines in extant megafauna are due to Homo sapiens rather than climate

The paper analyzes genome data to show that Homo sapiens, not climate, caused population declines in megafauna over the last 100,000 years.

The molecular evolution of spermatogenesis across mammals

This study analyzes single-nucleus transcriptomes from testes across eleven mammalian species to uncover molecular evolution patterns in spermatogenesis.

Evolutionary dynamics of pseudoautosomal region 1 in humans and great apes

This study quantifies evolutionary forces shaping PAR1 in humans and great apes, revealing mutation bias and recombination effects, but no sexually antagonistic selection.

Mutationathon: towards standardization in estimates of pedigree-based germline mutation rates

The paper evaluates variation in germline mutation rate estimates across labs using a standardized pedigree of rhesus macaques, highlighting methodological differences and the need for standardization.

Different historical generation intervals in human populations inferred from Neanderthal fragment lengths and patterns of mutation accumulation

The paper uses Neanderthal DNA fragment lengths in non-African genomes to infer historical differences in generation intervals across Eurasian populations.

Population dynamics of GC-changing mutations in humans and great apes

The paper examines how GC-biased gene conversion (gBGC) affects different mutation types in humans and great apes, finding stronger correlations with recombination for transitions than transversions.

The germline mutational process in rhesus macaque and its implications for phylogenetic dating

The paper estimates the germline mutation rate in rhesus macaques and finds paternal age correlation, male contribution dominance, and divergence time implications for primate phylogeny.

Extreme genetic signatures of local adaptation during plant colonization

The paper investigates genetic adaptations during the colonization of Japan by Lotus japonicus, identifying genomic regions and candidate genes associated with overwintering and flowering time traits.

Dynamic copy number evolution of X- and Y-linked ampliconic genes in human populations

The paper investigates copy number variation and coding variation of X- and Y-linked ampliconic genes in human populations using the Simons Genome Diversity Project, revealing extensive standing variation and rapid turnover.