Upregulated Fcrl5 disrupts B cell anergy and causes autoimmunity
C. Ono, S. Tanaka, K. Myouzen, T. Iwasaki, M. Ueda, Y. Oda, K. Yamamoto, Y. Kochi, Y. Baba
This study shows that upregulated Fcrl5 disrupts B cell anergy, leading to autoimmunity by activating autoreactive B cells and exacerbating autoimmune disease models.
bioRxiv · Jul 20, 2023 · PreprintImmunology