The clinical drug candidate ebselen attenuates inflammation and promotes microbiome recovery after antibiotic treatment for Clostridium difficile infection
M. Garland, A. J. Hryckowian, M. Tholen, S. Loscher, W. W. Van Treuren, K. Oresic Bender, J. L. Sonnenburg, M. Bogyo
This study shows ebselen reduces CDI recurrence and colitis in hamsters and promotes microbiome recovery without altering diversity in mice.
bioRxiv · Nov 1, 2019Microbiology