Dysregulation of the p53 pathway provides a therapeutic target in aggressive pediatric sarcomas with stem-like traits
L. Curylova, I. Staniczkova Zambo, J. Neradil, M. Kyr, N. Jurackova, S. Pavlova, K. Polaskova, P. Mudry, J. Sterba, R. Veselska, J. Skoda
This study shows that restoring p53 activity can target aggressive pediatric sarcomas with stem-like traits by inducing apoptosis in cancer cells while sparing healthy cells.
bioRxiv · Jan 17, 2024Cancer Biology