J. Neradil

Dysregulation of the p53 pathway provides a therapeutic target in aggressive pediatric sarcomas with stem-like traits

This study shows that restoring p53 activity can target aggressive pediatric sarcomas with stem-like traits by inducing apoptosis in cancer cells while sparing healthy cells.

Inhibiting mitochondrial translation overcomes multidrug resistance in MYC-driven neuroblastoma via OMA1-mediated integrated stress response