Author

J. Sterba

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Organism:mouse· 2 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

A. Dobias· 1 shared A. Kaprelyants· 1 shared D. Bednar· 1 shared D. Loginov· 1 shared F. Dycka· 1 shared G. Pinto· 1 shared I. Arefiev· 1 shared I. Staniczkova Zambo· 1 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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1 shared paperCancer Biology

A. Dobias

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

A Computational Workflow for Analysis of Missense Mutations in Precision Oncology

R. T. Khan, P. Pokorna, J. Stourac, S. Borko, I. Arefiev, J. Planas-Iglesias, A. Dobias, G. Pinto, V. Szotkowska, J. Sterba, O. Slaby, J. Damborsky, S. Mazurenko, D. Bednar

This paper presents a bioinformatics pipeline for analyzing missense mutations in oncogenic proteins, providing a probability score for functional impact and suggesting potential FDA/EMA-approved drugs.

bioRxiv · Jun 8, 2024Cancer Biology

Dysregulation of the p53 pathway provides a therapeutic target in aggressive pediatric sarcomas with stem-like traits

L. Curylova, I. Staniczkova Zambo, J. Neradil, M. Kyr, N. Jurackova, S. Pavlova, K. Polaskova, P. Mudry, J. Sterba, R. Veselska, J. Skoda

This study shows that restoring p53 activity can target aggressive pediatric sarcomas with stem-like traits by inducing apoptosis in cancer cells while sparing healthy cells.

bioRxiv · Jan 17, 2024Cancer Biology

Shotgun proteomic profiling of dormant, 'non-culturable' Mycobacterium tuberculosis

V. D. Nikitushkin, M. O. Shleeva, D. Loginov, F. Dycka, J. Sterba, A. Kaprelyants

This study uses proteomic profiling to analyze dormant Mycobacterium tuberculosis cells, identifying 468 differentially expressed proteins and metabolic pathways involved in persistence.

bioRxiv · Aug 6, 2021Microbiology