Author

K. R. N. V. Deepak

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

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A. Dumitru· 1 shared C. Zhang· 1 shared D. Alsteens· 1 shared H. Fan· 1 shared H. Liu· 1 shared M. Koehler· 1 shared

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2020-2020 · peak 1/yr

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1 shared paperBiochemistry

A. Dumitru

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1 paper

Recent·Most cited

BiochemistrybioRxivPreprintApr 3, 2020

High-affinity agonist binding to C5aR results from a cooperative two-site binding mechanism

A. Dumitru, K. R. N. V. Deepak, H. Liu…·D. Alsteens

This study identifies a cooperative two-site binding mechanism for C5aR activation using atomic force microscopy, steered molecular dynamics, and functional assays.

DOI 10.1101/2020.04.03.024018

humanexperimental assay

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