Author

K. R. Rouillard

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Organism:bacteria (other)· 1

Frequent Co-Authors

M. R. Markovetz· 3 shared D. B. Hill· 2 shared L. M. Plott· 2 shared C. P. Esther· 1 shared C. Roca· 1 shared D. Hill· 1 shared D. W. Bowman· 1 shared J. C. Schisler· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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3 shared papersMicrobiology

M. R. Markovetz

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3 papers

Recent·Most cited

Mucus polymer concentration and in vivo adaptation converge to define the antibiotic response of Pseudomonas aeruginosa during chronic lung infection

M. A. Greenwald, S. L. Meinig, L. M. Plott, C. Roca, M. G. Higgs, N. P. Vitko, M. R. Markovetz, K. R. Rouillard, J. Carpenter, M. Kesimer, D. B. Hill, J. C. Schisler, M. C. Wolfgang

This study shows that increased mucin and eDNA concentrations in mucus enhance Pseudomonas aeruginosa antibiotic tolerance, and establishes an in vitro model to replicate this tolerance observed in sputum.

bioRxiv · Dec 20, 2023 · PreprintMicrobiology

Combination Treatment to Improve Mucociliary Transport of Pseudomonas aeruginosa Biofilms

K. R. Rouillard, C. P. Esther, W. Kissner, L. M. Plott, D. W. Bowman, M. R. Markovetz, D. B. Hill

This paper tests combination treatments to disrupt Pseudomonas aeruginosa biofilms in mucus, finding that NP40, hyaluronic acid, and tobramycin most effectively increase mucociliary transport and reduce bacterial viability.

bioRxiv · Aug 14, 2023 · PreprintMicrobiology

Effects of mucin and DNA concentrations in airway mucus on Pseudomonas aeruginosa biofilm recalcitrance

K. R. Rouillard, W. J. Kissner, M. R. Markovetz, D. Hill

This study investigates how mucin and DNA concentrations in airway mucus affect Pseudomonas aeruginosa biofilm mechanical properties, finding that overall mucus concentration is the main factor influencing viscoelasticity.

bioRxiv · Mar 24, 2022Microbiology