Author

M. Kesimer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:host-pathogen & immune response· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1

Frequent Co-Authors

D. B. Hill· 2 shared M. R. Markovetz· 2 shared B. Button· 1 shared C. B. Morrison· 1 shared C. Ehre· 1 shared C. Roca· 1 shared D. Song· 1 shared E. Iverson· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersMicrobiology

D. B. Hill

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Mucus polymer concentration and in vivo adaptation converge to define the antibiotic response of Pseudomonas aeruginosa during chronic lung infection

M. A. Greenwald, S. L. Meinig, L. M. Plott, C. Roca, M. G. Higgs, N. P. Vitko, M. R. Markovetz, K. R. Rouillard, J. Carpenter, M. Kesimer, D. B. Hill, J. C. Schisler, M. C. Wolfgang

This study shows that increased mucin and eDNA concentrations in mucus enhance Pseudomonas aeruginosa antibiotic tolerance, and establishes an in vitro model to replicate this tolerance observed in sputum.

bioRxiv · Dec 20, 2023 · PreprintMicrobiology

Hyperconcentrated Mucus Unifies Submucosal Gland and Superficial Airway Dysfunction in Cystic Fibrosis

T. Kato, G. Radicioni, M. J. Papanikolas, G. V. Stoychev, M. R. Markovetz, K. Aoki, M. Porterfield, K. Okuda, S. M. B. Cardenas, R. C. Gilmore, C. B. Morrison, C. Ehre, K. A. Burns, K. K. White, T. A. Brennan, , R. C. Boucher

This study identifies hyperconcentrated mucus as a unifying mechanism for submucosal gland and superficial airway dysfunction in cystic fibrosis.

bioRxiv · Sep 22, 2021 · PreprintPathology

Membrane-Tethered Mucin 1 is Stimulated by Interferon in Multiple Cell Types and Antagonizes Influenza A Virus Infection in Human Airway Epithelium

E. Iverson, K. Griswold, D. Song, T. B. Gagliardi, K. Hamidzadeh, M. Kesimer, S. Sinha, M. Perry, G. A. Duncan, M. A. Scull

This study investigates how MUC1 interacts with influenza A virus in human airway epithelium and shows that MUC1 expression increases during infection, potentially limiting viral spread.

bioRxiv · Mar 11, 2021 · PreprintMicrobiology