Author

L. M. Plott

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:metabolism & bioenergetics· 1 Approach:statistical model· 1

Frequent Co-Authors

D. B. Hill· 3 shared M. R. Markovetz· 3 shared K. R. Rouillard· 2 shared C. P. Esther· 1 shared C. Roca· 1 shared D. A. Powers· 1 shared D. W. Bowman· 1 shared H. Wang· 1 shared

Activity by Year

2023-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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3 shared papersMicrobiology

D. B. Hill

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3 papers

Recent·Most cited

Clostridioides difficile-mucus interactions encompass shifts in gene expression, metabolism, and biofilm formation

K. L. Furtado, L. M. Plott, M. R. Markovetz, D. A. Powers, H. Wang, D. B. Hill, J. A. Papin, N. L. Allbritton, R. Tamayo

This study investigates how C. difficile uses host-derived mucus for growth, metabolism, and biofilm formation, revealing metabolic shifts and potential pathogenic mechanisms.

mSphere · Jun 25, 2024Peer-reviewedMicrobiology

Mucus polymer concentration and in vivo adaptation converge to define the antibiotic response of Pseudomonas aeruginosa during chronic lung infection

M. A. Greenwald, S. L. Meinig, L. M. Plott, C. Roca, M. G. Higgs, N. P. Vitko, M. R. Markovetz, K. R. Rouillard, J. Carpenter, M. Kesimer, D. B. Hill, J. C. Schisler, M. C. Wolfgang

This study shows that increased mucin and eDNA concentrations in mucus enhance Pseudomonas aeruginosa antibiotic tolerance, and establishes an in vitro model to replicate this tolerance observed in sputum.

bioRxiv · Dec 20, 2023 · PreprintMicrobiology

Combination Treatment to Improve Mucociliary Transport of Pseudomonas aeruginosa Biofilms

K. R. Rouillard, C. P. Esther, W. Kissner, L. M. Plott, D. W. Bowman, M. R. Markovetz, D. B. Hill

This paper tests combination treatments to disrupt Pseudomonas aeruginosa biofilms in mucus, finding that NP40, hyaluronic acid, and tobramycin most effectively increase mucociliary transport and reduce bacterial viability.

bioRxiv · Aug 14, 2023 · PreprintMicrobiology