Postnatal lymph node expansion of stromal progenitors towards reticular and CD34+ stromal cell subsets is determined by distinct transcriptional programs
J. Pezoldt, C. Wiechers, M. Litovchenko, M. Biocanin, M. Zou, K. Sitnik, M. Beckstette, W. Chen, V. Gardeux, S. Floess, M. Ebel, J. Russeil, P. Arampatzi, E. Vafardanejad, A.-E. Saliba, , J. Huehn
The paper identifies distinct transcriptional programs driving the expansion of stromal progenitors in mesenteric lymph nodes, revealing Irf3's role in FRC differentiation and microbiota-independent epigenomic signatures.
bioRxiv · Jun 6, 2021 · PreprintImmunology