Dissecting reprogramming heterogeneity at single-cell resolution using scTF-seq
W. Liu, W. Saelens, P. Rainer, M. Biocanin, V. Gardeux, A. Gralak, G. van Mierlo, J. Russeil, T. Liu, W. Chen, B. Deplancke
The paper introduces scTF-seq, a method to study TF dose-dependent reprogramming in mouse MSCs, revealing heterogeneity in cell fate and TF sensitivity.
bioRxiv · Jan 30, 2024Cell Biology