Author

S. Floess

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Research Focus:differential expression· 2 Assay:DNA methylation· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Approach:deep learning· 1

Frequent Co-Authors

J. Huehn· 3 shared M. Beckstette· 2 shared A. Bonifacius· 1 shared A. Keller· 1 shared A. Schippers· 1 shared A.-E. Saliba· 1 shared B. Denecke· 1 shared B. Deplancke· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersImmunology

J. Huehn

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Author profile →

3 papers

Recent·Most cited

CREB REGULATES FOXP3+ST-2+ TREGS WITH ENHANCED IL-10 PRODUCTION

S. Hebbar Subramanyam, J. Hriczko, S. Schulz, T. Look, T. Goodarzi, T. Clarner, M. Scheld, M. Kipp, E. Verjans, S. Boell, C. Neullens, I. Costa, Z. Li, L. Gan, B. Denecke, , K. Tenbrock

This study shows that CREB knockout in Foxp3+ Tregs increases IL-10 and ST-2 expression, enhancing their suppressive function and preventing gut inflammation.

bioRxiv · Jun 29, 2024Immunology

DNA methylation profiling identifies TBKBP1 as potent amplifier of cytotoxic activity in CMV-specific human CD8+ T cells

Z. Yu, V. Sasidharan-Nair, A. Bonifacius, F. Khan, T. Buchta, M. Beckstette, J. Niemz, P. Hilgendorf, B. Pietzsch, P. Mausberg, A. Keller, C. S. Falk, D. S. Busch, M. Brinkmann, K. Schober, , J. Huehn

The paper identifies TBKBP1 as a key gene whose demethylation enhances cytotoxic activity in CMV-specific CD8+ T cells, suggesting it as a therapeutic target.

bioRxiv · Nov 6, 2023Immunology

Postnatal lymph node expansion of stromal progenitors towards reticular and CD34+ stromal cell subsets is determined by distinct transcriptional programs

J. Pezoldt, C. Wiechers, M. Litovchenko, M. Biocanin, M. Zou, K. Sitnik, M. Beckstette, W. Chen, V. Gardeux, S. Floess, M. Ebel, J. Russeil, P. Arampatzi, E. Vafardanejad, A.-E. Saliba, , J. Huehn

The paper identifies distinct transcriptional programs driving the expansion of stromal progenitors in mesenteric lymph nodes, revealing Irf3's role in FRC differentiation and microbiota-independent epigenomic signatures.

bioRxiv · Jun 6, 2021 · PreprintImmunology