Author

J. Pezoldt

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Bioengineering· 1 Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell type annotation· 3 Organism:human· 3 Assay:scRNA-seq· 3 Assay:bulk RNA-seq· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Approach:statistical model· 2

Frequent Co-Authors

B. Deplancke· 5 shared J. Russeil· 4 shared V. Gardeux· 4 shared D. Alpern· 2 shared M. Biocanin· 2 shared W. Saelens· 2 shared A. Chrisnandy· 1 shared A. Kratzel· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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5 shared papersMicrobiology

B. Deplancke

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

A human omentum-specific mesothelial-like stromal population inhibits adipogenesis through IGFBP2 secretion

R. Ferrero, P. Rainer, J. Russeil, M. Zachara, J. Pezoldt, G. van Mierlo, V. Gardeux, W. Saelens, D. Alpern, L. Favre, S. Mantziari, T. Zingg, N. Pitteloud, M. Suter, M. Matter, , B. Deplancke

The paper identifies an omental-specific stromal population that inhibits adipogenesis via IGFBP2 secretion in human adipose tissue.

bioRxiv · May 1, 2023Cell Biology

Pseudomonas aeruginosa contracts mucus to form biofilms in tissue-engineered human airways

T. Rossy, T. Distler, J. Pezoldt, J. Kim, L. Tala, N. Bouklas, B. Deplancke, A. Persat

This study shows Pseudomonas aeruginosa forms mucus-associated biofilms in human airway models by contracting mucus using type IV pili.

bioRxiv · May 26, 2022 · PreprintMicrobiology

Postnatal lymph node expansion of stromal progenitors towards reticular and CD34+ stromal cell subsets is determined by distinct transcriptional programs

J. Pezoldt, C. Wiechers, M. Litovchenko, M. Biocanin, M. Zou, K. Sitnik, M. Beckstette, W. Chen, V. Gardeux, S. Floess, M. Ebel, J. Russeil, P. Arampatzi, E. Vafardanejad, A.-E. Saliba, , J. Huehn

The paper identifies distinct transcriptional programs driving the expansion of stromal progenitors in mesenteric lymph nodes, revealing Irf3's role in FRC differentiation and microbiota-independent epigenomic signatures.

bioRxiv · Jun 6, 2021 · PreprintImmunology

Deterministic scRNA-seq of individual intestinal organoids reveals new subtypes and coexisting distinct stem cell pools

J. Bues, M. Biocanin, J. Pezoldt, R. Dainese, A. Chrisnandy, S. Rezakhani, W. Saelens, V. Gardeux, R. Gupta, J. Russeil, Y. Saeys, E. Amstad, M. Claassen, M. Lutolf, B. Deplancke

The paper introduces DisCo, a deterministic scRNA-seq method for small tissue samples, revealing new intestinal organoid subtypes and stem cell populations.

bioRxiv · May 19, 2020 · PreprintBioengineering

Disparate temperature-dependent virus - host dynamics for SARS-CoV-2 and SARS-CoV in the human respiratory epithelium

P. V'kovski, M. Gultom, J. N. Kelly, S. Steiner, J. Russeil, B. Mangeat, E. Cora, J. Pezoldt, M. Holwerda, A. Kratzel, L. Laloli, M. Wider, J. Portmann, T. T. N. Thao, N. Ebert, , R. Dijkman

This study compares temperature-dependent replication and immune response dynamics of SARS-CoV-2 and SARS-CoV in human airway epithelial cells, highlighting differences in their antiviral responses and transmission efficiency.

bioRxiv · Apr 27, 2020Microbiology