In Vivo Dual RNA-Seq Analysis Reveals the Basis for Differential Tissue Tropism of Clinical Isolates of Streptococcus pneumoniae
V. Minhas, R. Aprianto, L. J. McAllister, H. Wang, S. C. David, K. T. McLean, I. Comerford, S. R. McColl, J. C. Paton, J.-W. Veening, C. Trappetti
This study uses dual RNA-seq to show how a single SNP in Streptococcus pneumoniae affects bacterial and host gene expression, leading to differential tissue tropism and disease outcomes.
bioRxiv · Dec 3, 2019Microbiology