Author

K. W. Graepel

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

M. R. Denison· 2 shared N. R. Sexton· 2 shared X. Lu· 2 shared E. C. Smith· 1 shared J. B. Case· 1 shared M. L. Agostini· 1 shared R. Elliott· 1 shared S. R. Weiss· 1 shared

Activity by Year

2017-2019 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 31 mutual co-author links

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2 shared papersMicrobiology

M. R. Denison

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2 papers

Recent·Most cited

Fitness barriers limit reversion of a proofreading-deficient coronavirus

K. W. Graepel, M. L. Agostini, X. Lu, N. R. Sexton, M. R. Denison

This study shows that reversion of a proofreading-deficient coronavirus (ExoN-AA) is hindered by fitness barriers, as compensatory mutations outside the ExoN motif I are more advantageous than partial reversion.

bioRxiv · Apr 26, 2019Microbiology

Mouse hepatitis virus nsp14 exoribonuclease activity is required for resistance to innate immunity

J. B. Case, Y. Li, R. Elliott, X. Lu, K. W. Graepel, N. R. Sexton, E. C. Smith, S. R. Weiss, M. R. Denison

This study shows that MHV nsp14 exoribonuclease activity is necessary for resisting innate immunity by affecting viral RNA and modifications.

bioRxiv · Aug 29, 2017Microbiology