Cardioprotection by the mitochondrial unfolded protein response (UPRmt) is mediated by activating transcription factor 5 (ATF5)
Y. T. Wang, Y. Lim, M. N. McCall, C. M. Haynes, K. W. Nehrke, P. S. Brookes
This study shows that ATF5 is required for cardioprotection induced by UPRmt activators against ischemia-reperfusion injury.
bioRxiv · Nov 9, 2018Cell Biology