Author

K. Wikenheiser-Brokamp

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:human· 1 Organism:mouse· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

A. A. Zhang· 2 shared E. J. Kopras· 2 shared E. P. Smith· 2 shared E. Y. Zhang· 2 shared F. X. McCormack· 2 shared J. J. Yu· 2 shared M. Guo· 2 shared N. Gupta· 2 shared

Activity by Year

2022-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCancer Biology

A. A. Zhang

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Integrative Single Cell Multiomic Profiling Analysis Reveals HOX-PBX Gene Regulatory Network Contributing to the Survival of mTOR Hyperactive Cells

T. F. Olatoke, A. Wagner, A. A. Astrinidis, M. Guo, E. Y. Zhang, A. A. Zhang, U. Mattam, K. Chilton, E. J. Kopras, N. Gupta, E. P. Smith, M. Karbowniczek, M. M. Markiewski, K. Wikenheiser-Brokamp, J. A. Whitsett, , J. J. Yu

This study identifies PBX1 as a critical regulator of LAM progression by analyzing scRNA-seq data and validating its role in LAM cell survival and lung colonization.

bioRxiv · Sep 27, 2022 · PreprintCancer Biology

Dysregulation of Acid Ceramidase-mediated Sphingolipid Metabolism Contributes to Tumor Progression in Tuberous Sclerosis Complex

A. Astrinidis, C. Li, E. Y. Zhang, X. Zhao, S. Zhao, M. Guo, R. Huang, A. A. Zhang, E. J. Kopras, N. Gupta, E. P. Smith, E. Fugate, D. Lindquist, K. Wikenheiser-Brokamp, K. D. Setchell, , J. J. Yu

This study identifies dysregulated sphingolipid metabolism in TSC2-null cells and tumors, showing that ASAH1 inhibition reduces cell viability and tumor growth in TSC and LAM.

bioRxiv · Sep 25, 2022 · PreprintCell Biology