Endothelial restoration of CAD GWAS gene PLPP3 by nanomedicine suppresses YAP/TAZ activity and reduces atherosclerosis in vivo
J. Zhu, C.-F. Yeh, R.-T. Huang, T.-H. Lee, T.-P. Shentu, D. Wu, K.-C. Yang, Y. Fang
This paper develops a nanomedicine approach to restore PLPP3 in endothelial cells, reducing YAP/TAZ activity and atherosclerosis in mice.
bioRxiv · May 6, 2021 · PreprintBioengineering