Author

Y.-S. Huang

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Plant Biology· 2 Bioengineering· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:cell signaling & trafficking· 3 Research Focus:cell type annotation· 3 Organism:mouse· 3 Assay:proteomics· 3 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

N. Hsu· 2 shared S.-R. Hong· 2 shared Y. C. LIN· 2 shared Y.-C. Chang· 2 shared Y.-C. Chiang· 2 shared A. Toghani· 1 shared A. Y.-T. Wu· 1 shared B.-J. Chiang· 1 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersBioengineering

N. Hsu

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Functional divergence shaped the network architecture of plant immune receptors

C.-Y. Huang, Y.-S. Huang, Y. Sugihara, H.-Y. Wang, L.-T. Huang, J. C. Lopez-Agudelo, Y.-F. Chen, K.-Y. Lin, B.-J. Chiang, A. Toghani, J. Kourelis, L. Derevnina, C.-H. Wu

The paper shows how functional divergence in NRC3 variants shapes the genetic architecture of the NLR network in solanaceous plants, leading to subfunctionalization and increased immune system complexity.

bioRxiv · Dec 12, 2023 · PreprintPlant Biology

Actin filaments act as a size-dependent diffusion barrier around centrosomes

H. Cheng, Y.-L. Kao, L. Sharma, W.-T. Yang, S.-H. Huang, H.-R. Lin, Y.-S. Huang, C.-L. Kao, L.-W. Yang, R. Bearon, Y. C. LIN

The paper quantifies size-dependent diffusion barriers around centrosomes, showing branched actin filaments restrict molecule access based on size.

bioRxiv · Oct 21, 2021 · PreprintCell Biology

A Positive Regulatory Feedback Loop Between 1 EKLF/ KLF1 and TAL1/SCL2 Sustaining the Erythropoiesis

C.-H. Hung, Y.-S. Huang, T.-L. Lee, K.-C. Yang, Y.-C. Shyu, S.-C. Wen, M.-J. Lu, S. Yuan, C.-K. J. Shen

The paper identifies a positive feedback loop between EKLF/KLF1 and TAL1/SCL in sustaining erythropoiesis through direct transcriptional regulation.

bioRxiv · Apr 8, 2021Cell Biology

The histone deacetylase HDA15 interacts with MAC3A and MAC3B to regulate intron retention of ABA-responsive genes

Y.-T. Tu, C.-Y. Chen, Y.-S. Huang, M.-R. Yen, J.-W. A. Hsieh, P.-Y. Chen, K. Wu

The paper identifies HDA15's interaction with MAC3A and MAC3B in regulating ABA-responsive intron retention and histone acetylation levels.

bioRxiv · Nov 17, 2020 · PreprintPlant Biology

Hyperpolyploidization of hepatocyte initiates preneoplastic lesion formation in the liver

H.-W. Chao, H. Lin, Y.-S. Huang, J.-M. Fustin, M. Doi, H. Chen, H.-H. Lai, S.-H. Lin, Y.-L. Lee, P.-C. King, H.-S. Hou, H.-W. Chen, P.-Y. Young

This study shows that hyperpolyploidization of hepatocytes in the centrilobular region initiates preneoplastic lesion formation, with AURKB upregulation and phosphorylation driving this process in HCC development.

bioRxiv · Aug 23, 2020Pathology

Sonogenetic modulation of cellular activities using an engineered auditory-sensing protein

Y.-S. Huang, C.-H. Fan, N. Hsu, C.-Y. Wu, C.-Y. Chang, S.-R. Hong, Y.-C. Chang, A. Y.-T. Wu, V. Guo, Y.-C. Chiang, W.-C. Hsu, N.-H. Chiu, L. Chen, C. P.-K. Lai, C.-K. Yeh, Y. C. LIN

This paper introduces a sonogenetic method using an engineered auditory-sensing protein to control cellular activities with ultrasound, showing it can stimulate neurons in deep brain regions non-invasively.

bioRxiv · May 3, 2019Bioengineering

Spatiotemporal manipulation of ciliary glutamylation reveals its roles in intraciliary trafficking and Hedgehog signaling

S.-R. Hong, C.-L. Wang, Y.-S. Huang, Y.-C. Chang, Y.-C. Chang, G. V. Pusapati, C.-Y. Lin, N. Hsu, H.-C. Cheng, Y.-C. Chiang, W.-E. Huang, N. C. Shaner, R. Rohatgi, T. Inoue, Y.-C. Lin

The paper develops a method to rapidly deplete tubulin glutamylation in primary cilia, revealing its role in intraflagellar transport and Hedgehog signaling without affecting other PTMs.

bioRxiv · Mar 15, 2018Cell Biology