Author

K.-L. Laugwitz

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Research Focus:cell-cell communication· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:scRNA-seq· 2 Assay:bulk RNA-seq· 1 Approach:deep learning· 1

Frequent Co-Authors

A. Moretti· 3 shared G. Santamaria· 3 shared C. Kupatt· 2 shared D. Zawada· 2 shared N. Klymiuk· 2 shared T. Dorn· 2 shared A. B. Meier· 1 shared A. Baehr· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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3 shared papersCell Biology

A. Moretti

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Author profile →

3 papers

Recent·Most cited

Increased pulmonary monocyte infiltration and attenuated phagocytosis defines perinatal dysfunction of innate immunity in Cystic Fibrosis

F. Jaudas, F. Bartenschlager, B. Shashikadze, G. Santamaria, A. Schnell, N. Naumann-Barsch, H. Bruns, S. Y. Graeber, A. Baehr, M. Cambra-Bort, M. Stirm, J. B. Stoeckl, S. Krebs, H. Blum, C. Schulz, , N. Klymiuk

The paper identifies increased monocyte infiltration and reduced phagocytosis in CF lungs at birth, suggesting innate immune dysfunction and the need for early treatment.

bioRxiv · Sep 11, 2023 · PreprintImmunology

Retinoic acid signaling modulation guides in vitro specification of human heart field-specific progenitor pools

D. Zawada, J. Kornherr, A. B. Meier, G. Santamaria, T. Dorn, D. Ortmann, M. Lachmann, M. Ortiz, S. C. Harmer, M. Nobles, A. Tinker, R. A. Pedersen, P. Grote, K.-L. Laugwitz, A. Moretti, A. Goedel

This study shows that modulating retinoic acid signaling in human pluripotent stem cells generates heart field-specific progenitors, including a novel juxta-cardiac field, and identifies transcriptional dysregulation in a patient with hypoplastic left heart syndrome.

bioRxiv · May 30, 2022Cell Biology

Primate heart regeneration via migration and fibroblast repulsion by human heart progenitors

C. Schneider, K. S. Foo, M. T. De Angelis, G. Santamaria, F. Reiter, T. Dorn, A. Bähr, Y. L. Tsoi, P. Hoppmann, I. My, A. Meier, V. Jurisch, N. Hornaschewitz, S. Schwarz, K. Lu, , K.-L. Laugwitz

This study shows human heart progenitors can regenerate primate hearts by migrating to injury sites, repelling fibroblasts, and replacing damaged tissue through CXCL12/CXCR4 and SLIT2/ROBO1 signaling.

bioRxiv · Jul 3, 2020 · PreprintCell Biology