Three neurotransmitters regulate diverse inhibitory and excitatory Parvalbumin interneuron circuits in the dorsal horn
Mark A. Gradwell, KA Boyle, Tyler J. Browne, Allen C. Dickie, AM Bell, Jacklyn Leonardo, Fernanda S. Peralta Reyes, KM Smith, Rj Callister, Christopher V. Dayas, David I. Hughes, Brett Anthony Graham
The paper identifies that excitatory and inhibitory parvalbumin interneurons in the spinal dorsal horn form distinct circuits and that excitatory interneurons contribute to mechanical hypersensitivity under pathological conditions.
bioRxiv · Dec 23, 2020 · PreprintNeuroscience