RNA switch model for localization and translation of the myelin basic protein mRNA
Ved V. Topkar, Yuan Wu, Lana T. Ho, Nicholas Ambiel, Alex Valenzuela, Kailee Yoshimura, J. Bradley Zuchero, Meng‐meng Fu, Rhiju Das
The paper identifies a structured RNA region, MLS, necessary and sufficient for Mbp mRNA transport to oligodendrocyte projections and shows it interacts with hnRNP-F, suggesting a structural switch model for mRNA transport to translation.
bioRxiv · Nov 19, 2025 · PreprintCell Biology