Author

Ved V. Topkar

Stanford UniversityORCID 0000-0001-6123-2065Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Assay:metagenomics· 1 Approach:microscopy & imaging analysis· 1 Assay:multiome· 1 Assay:proteomics· 1

Frequent Co-Authors

Rhiju DasiD· 2 shared Adele XuiD· 1 shared Alex Valenzuela· 1 shared Alicia SolórzanoiD· 1 shared Andrew M. WatkinsiD· 1 shared Bojan Tunguz· 1 shared Christian A. ChoeiD· 1 shared Craig H. KerriD· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersCell Biology

Rhiju DasORCID

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2 papers

Recent·Most cited

Cell BiologybioRxivPreprintNov 19, 2025

RNA switch model for localization and translation of the myelin basic protein mRNA

Ved V. Topkar, Yuan Wu, Lana T. Ho…·Rhiju Das

The paper identifies a structured RNA region, MLS, necessary and sufficient for Mbp mRNA transport to oligodendrocyte projections and shows it interacts with hnRNP-F, suggesting a structural switch model for mRNA transport to translation.

3 citations

ratmetagenomics

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Molecular BiologyNature CommunicationsPeer-reviewedMar 22, 2022

Combinatorial optimization of mRNA structure, stability, and translation for RNA-based therapeutics

Kathrin Leppek, Gun Woo Byeon, Wipapat Kladwang…·Rhiju Das

This study develops PERSIST-seq and In-line-seq to optimize mRNA stability and translation, finding that in-cell stability is more critical than ribosome load for protein output.

400 citationstop 1%

humanmultiome

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