Absence of MBP 3' UTR in Mice Disrupts mRNA Transport, Myelination, and Motor Learning
Joseph C. Nowacki, Haidyn L. Bulen, Lindsey M. Meservey…·Meng‐meng Fu
Author
National Institutes of HealthORCID 0000-0003-4958-0424Unclaimed ORCID profile · follow to get notified of new preprints
5 papers
Recent·Most cited
Joseph C. Nowacki, Haidyn L. Bulen, Lindsey M. Meservey…·Meng‐meng Fu
Ved V. Topkar, Yuan Wu, Lana T. Ho…·Rhiju Das
The paper identifies a structured RNA region, MLS, necessary and sufficient for Mbp mRNA transport to oligodendrocyte projections and shows it interacts with hnRNP-F, suggesting a structural switch model for mRNA transport to translation.
Meghan E. Wynne, William E. Barclay, Dharshini Gopal…·Meng‐meng Fu
This study investigates the cytoskeletal organization of astrocytes and shows how microtubule and actin structures contribute to their complex branching morphology.
Phillip S. Gross, Violeta Durán‐Laforet, Lana T. Ho…·Jeffrey K. Huang
This study shows that senescent microglia impair remyelination in young mice but not aged mice, with CCL11 in SASP inhibiting oligodendrocyte maturation.
Shahrnaz Kemal, Hunter S. Richardson, Thomas S. McAlear…·Meng‐meng Fu
This paper shows TPPP forms liquid condensates and aggregates in Multiple System Atrophy, linking its condensate property to microtubule nucleation and disease pathology.