Author

Lana T. Ho

University of California, BerkeleyORCID 0000-0002-6846-2127Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Approach:experimental assay· 1 Assay:metagenomics· 1 Approach:microscopy & imaging analysis· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Meng‐meng FuiD· 2 shared Alex Valenzuela· 1 shared Dorothy P. SchaferiD· 1 shared Enrique ÁlvareziD· 1 shared George S. MelchoriD· 1 shared J. Bradley ZucheroiD· 1 shared Jason R. PlemeliD· 1 shared Jeffrey K. HuangiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersCell Biology

Meng‐meng FuORCID

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2 papers

Recent·Most cited

RNA switch model for localization and translation of the myelin basic protein mRNA

Ved V. Topkar, Yuan Wu, Lana T. Ho, Nicholas Ambiel, Alex Valenzuela, Kailee Yoshimura, J. Bradley Zuchero, Meng‐meng Fu, Rhiju Das

The paper identifies a structured RNA region, MLS, necessary and sufficient for Mbp mRNA transport to oligodendrocyte projections and shows it interacts with hnRNP-F, suggesting a structural switch model for mRNA transport to translation.

bioRxiv · Nov 19, 2025 · PreprintCell Biology

Senescent-like microglia limit remyelination through the senescence associated secretory phenotype

Phillip S. Gross, Violeta Durán‐Laforet, Lana T. Ho, George S. Melchor, Sameera Zia, Zeeba Manavi, William E. Barclay, Sung Hyun Lee, Nataliia V. Shults, Sean Selva, Enrique Álvarez, Jason R. Plemel, Meng‐meng Fu, Dorothy P. Schafer, Jeffrey K. Huang

This study shows that senescent microglia impair remyelination in young mice but not aged mice, with CCL11 in SASP inhibiting oligodendrocyte maturation.

Nature Communications · Mar 7, 2025Peer-reviewedNeuroscience