Deep Profiling of EV Long RNAs Reveals Biofluid-Specific Transcriptomes and Splicing Landscapes
Sudipto K. Chakrabortty, Shuran Xing, Sinead Nguyen, Allan George, Dulaney L. Miller, Kailey Babcock, Kyle Manning, T. Jeffrey Cole, Emily Mitsock, J. Christian J. Ray, Sivakumar Gowrisankar, Johan Skog
The paper develops a targeted RNA capture method to enhance detection of long RNAs in EVs from human biofluids, revealing biofluid-specific transcriptomes and splicing patterns.
bioRxiv · Aug 5, 2025 · PreprintGenomics