T. Jeffrey Cole

Extracellular Vesicle Gene Expression Enables Sensitive Detection of Colorectal Neoplasia

This study compares EV transcriptomics, proteomics, and cfDNA methylation for detecting colorectal neoplasia, finding EV transcriptomics most sensitive for advanced adenomas and CRC.

Salivary Extracellular Vesicle RNA Profiling Reveals Biomarkers for Sjogrens

This study identifies RNA biomarkers in salivary extracellular vesicles for diagnosing Sjogrens subtypes with high sensitivity and specificity.

Deep Profiling of EV Long RNAs Reveals Biofluid-Specific Transcriptomes and Splicing Landscapes

The paper develops a targeted RNA capture method to enhance detection of long RNAs in EVs from human biofluids, revealing biofluid-specific transcriptomes and splicing patterns.

FUSTr: a tool to find gene Families Under Selection in Transcriptomes

FUSTr identifies gene families under positive selection in transcriptomes by analyzing isoform patterns and is validated on spider toxin families and simulated data.