Extracellular Vesicle Gene Expression Enables Sensitive Detection of Colorectal Neoplasia
Sivakumar Gowrisankar, J. Christian J. Ray, Sinead Nguyen, Christopher J. Benway, Shuran Xing, Allan George, Dulaney L. Miller, Kyle Manning, Yang Yang, T. Jeffrey Cole, Emily Mitsock, Devin Perez, Luanna Dealmeida, Julia Doo, Pawan Upadhyay, , Johan Skog
This study compares EV transcriptomics, proteomics, and cfDNA methylation for detecting colorectal neoplasia, finding EV transcriptomics most sensitive for advanced adenomas and CRC.
bioRxiv · Aug 14, 2025 · PreprintGenomics