XRCC1 mediates PARP1- and PAR-dependent recruitment of PARP2 to DNA damage sites
Xiaohui S. Lin, Kay Sze Karina Leung, Kaitlynn F. Wolfe, Nicolas Call, Seema Khattri Bhandari, Xiaoyu Huang, Brian J. Lee, Alan E. Tomkinson, Shan Zha
This study shows that XRCC1 facilitates PARP1-mediated recruitment of PARP2 to DNA damage sites through PAR binding and interaction with PARP2.
Nucleic Acids Research · Feb 8, 2025Peer-reviewedCell Biology