Author

Kay Sze Karina Leung

Columbia University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Assay:DNA methylation· 2 Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

Alan E. TomkinsoniD· 2 shared Brian J. LeeiD· 2 shared Seema Khattri Bhandari· 2 shared Shan ZhaiD· 2 shared Xiaoyu HuangiD· 2 shared Alina VaitsiankovaiD· 1 shared Demis MenolfiiD· 1 shared Dipika GuptaiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCell Biology

Alan E. TomkinsonORCID

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2 papers

Recent·Most cited

Cell BiologyNucleic Acids ResearchPeer-reviewedFeb 8, 2025

XRCC1 mediates PARP1- and PAR-dependent recruitment of PARP2 to DNA damage sites

Xiaohui S. Lin, Kay Sze Karina Leung, Kaitlynn F. Wolfe…·Shan Zha

This study shows that XRCC1 facilitates PARP1-mediated recruitment of PARP2 to DNA damage sites through PAR binding and interaction with PARP2.

22 citationstop 3%

humanDNA methylation

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GeneticsMolecular CellPeer-reviewedOct 1, 2024

Inactive Parp2 causes Tp53-dependent lethal anemia by blocking replication-associated nick ligation in erythroblasts

Xiaohui Lin, Dipika Gupta, Alina Vaitsiankova…·Shan Zha

The paper shows that inactive PARP2 causes Tp53-dependent lethal anemia by blocking replication-associated nick ligation in erythroblasts, explaining PARPi-induced hematological toxicities.

27 citationstop 5%

mouseDNA methylation

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