Scg2 drives reorganization of the corticospinal circuit with spinal premotor interneurons to recover motor function after stroke
Tokiharu Sato, Yuka Nakamura, Kana Hoshina, Ken‐ichi Inoue, Masahiko Takada, Masato Yano, Hitoshi Matsuzawa, Masaki Ueno
This study identifies Scg2 as a secretory protein that promotes axon rewiring and motor recovery after stroke by enhancing axon growth through cAMP and S6 signaling.
Nature Communications · Jun 9, 2026Peer-reviewedNeuroscience