Cortical excitatory and inhibitory neuron deficits may underlie the cognitive and social impairments in a mouse model of schizophrenia with exonic Reln deletion
Youyun Zhu, Kanako Kitagawa, Daisuke Mori, Tetsuo Matsuzaki, Taku Nagai, Toshitaka Nabeshima, Sayaka Takemoto‐Kimura, Hiroaki Ikesue, Norio Ozaki, Hiroyuki Mizoguchi, Kiyofumi Yamada
This paper investigates the role of Reelin in schizophrenia by analyzing a mouse model with exonic Reln deletion, finding deficits in excitatory and inhibitory neurons and suggesting therapeutic potential for Reelin replacement.
European Journal of Pharmacology · Nov 26, 2025Peer-reviewedAnimal Behavior & Cognition