Toshitaka Nabeshima

This study identifies KCNQ2/3 potassium channels as regulators of synaptic remodeling during withdrawal, showing their activation can suppress cocaine-seeking behavior.

This study compares the effects of fasudil and KD025 on serotonin and dopamine release in the nucleus accumbens of mice, finding distinct roles for Rho-kinase 1 and 2 in neurotransmitter regulation.

This study shows that the selective ROCK2 inhibitor KD025 has antipsychotic-like effects and fewer side effects in schizophrenia models.

This paper investigates the role of Reelin in schizophrenia by analyzing a mouse model with exonic Reln deletion, finding deficits in excitatory and inhibitory neurons and suggesting therapeutic potential for Reelin replacement.

This study identifies Twinfilin-1 phosphorylation as a key component of reelin signaling that regulates actin dynamics and spine development in neurons.

This study shows high salt intake causes cognitive impairment in mice through the angiotensin II-AT1 and prostaglandin E2-EP1 systems, which can be mitigated by losartan or EP1 gene knockout.